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Coenzyme Q-10 (CoQ10)

What is Coenzyme Q10?

Coenzyme Q10 (ubiquinone) is a fat-soluble vitamin-like substance present in every cell of the body. It is a strong antioxidant. CoQ10 is an essential component of the mitochondria - the energy producing unit of the cells of our body. It is involved in the manufacture of ATP (adenosine tri-phosphate) in the mitochondria, which are located in every cell membrane. Cellular energy in the form of ATP is required for all physiological functions.

Our bodies are able to produce some amount of the CoQ10 that we need. The rest is synthesized from the foods we eat. Coenzyme Q10 is synthesized in all tissues and in healthy individuals normal levels are maintained both by CoQ10 intake and by the body's synthesis of CoQ10. It has no known toxicity or side effects.

CoQ10 levels decrease with age and are low in people with some chronic diseases such as heart conditions, muscular dystrophies, Parkinson's disease, diabetes. Some prescription medications may also lower CoQ10 levels. Levels of CoQ10 in the body can be increased by taking CoQ10 supplements.

Uses for Coenzyme Q10

Because CoQ10 is essential for the production of cellular energy, CoQ10 enhances stamina and improves the body's overall state of health. It also protects against free radicals, strengthens the immune system and fosters resistance to circulatory and heart problems disease.

Coenzyme Q-10 is used for:

  • High blood pressure (hypertension)
  • Neurodegenerative disorders (Alzheimer's disease)
  • Angina (chest pain from clogged heart arteries)
  • Cardiomyopathy (dilated, hypertrophic)
  • Exercise performance
  • Gum disease (periodontitis)
  • Heart attack (acute myocardial infarction)
  • Heart protection during surgery
  • Muscular dystrophies
  • Macular degeneration
  • Chronic fatigue syndrome
  • Lipid lowering (adjunct to statins)

Heart-strengthening benefits

The most exciting use of coenzyme Q10 is for the prevention and treatment of cardiovascular disorders. There have been over 35 placebo-controlled trials using CoQ10 in cardiovascular disease involving thousands of patients.

CoQ10 is known to be highly concentrated in heart muscle cells due to the high energy requirements of these cells. Deficiency of CoQ10 in the blood and heart muscle has been documented in various heart disorders. Specifically, congestive heart failure has been strongly correlated with significantly low blood and tissue levels of CoQ10.

Studies have found that taking coenzyme Q-10 after a heart attack (myocardial infarction) can help reduce the risk of future cardiac events, including non-fatal myocardial infarction.

Coenzyme Q was approved in Japan in 1974 to treat congestive heart failure, and has also been approved in Sweden, Italy, Denmark, and Canada.

Italian doctors noted impressive improvements after four weeks of giving CoQ10 (100 mg three times daily) to 21 patients with severe heart failure. CoQ10 supplements, ranging from 60-300 mg daily, can significantly improve the heart's ability to pump blood.

Coenzyme Q10 food sources

Coenzyme Q10 can be synthesized in the body from whole foods rich in tyrosine and phenylalanine, vitamin E, folic acid, and vitamins B-1 and B-6.

Coenzyme Q10 is naturally present in small amounts in a wide variety of foods. But is particularly high in fish and meat. The highest dietary sources of Coenzyme Q10 come from fresh sardines and mackerel, the heart, liver and meat of beef, lamb and pork along with eggs.

There are also plenty of vegetable sources of Coenzyme Q10. The richest are spinach, broccoli, peanuts, wheat germ and whole grains. However, the amount is significantly smaller than that found in meats. Also, it is important to note that these foods must be raw, fresh and unprocessed - no milling, canning, preserving, freezing.


CoQ10 may lower blood sugar levels. Caution is advised in people with diabetes or hypoglycemia.

CoQ10 may lower blood pressure. It can increase the effects of medications used to lower blood pressure.

Product Package Price Buy
Well Heart 1 Month Supply (30 capsules) $19.95
Well Heart 3 Months Supply (90 capsules) $39.95


Coenzyme Q10 from Botanic Choice

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  • Morisco C, Trimarco B, Condorelli M. Effect of coenzyme Q10 therapy in patients with congestive heart failure: a long-term multicenter randomized study. Clin Investig. 1993;71(8 Suppl):S134-6. NCBI


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April 10, 2020